Natural History of Treated Neurocysticercosis and Long-Term Outcomes

This observational study is looking at how neurocysticercosis (NCC), a brain disease caused by the pork tapeworm, progresses in people who are receiving treatment. Researchers want to understand the disease's course during and after treatment with medications like praziquantel and/or albendazole, along with anti-inflammatory drugs. They will also look for new ways to detect the infection and understand how the parasite interacts with the body. You may be able to join if you are 3 years or older and have proven or likely NCC. If you are 18 or older and have been exposed to NCC, you might also be eligible. The study aims to describe how the disease appears, how it affects people, and how they respond to treatment over a long period.

Study design
This is an observational study with a planned enrollment of 500 participants. It is designed to follow participants with cysticercosis during and after treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed long-term to characterize the biochemical and clinical course of neurocysticercosis during and after treatment.

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NCT00001205

Natural History of Treated Neurocysticercosis and Long-Term Outcomes

Recruiting
Not specifiedAges 3–99Observational
National Institute of Allergy and Infectious Diseases (NIAID)
~500 participants
Updated 2026-07-28 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The primary objective is to characterize the biochemical and clinical course of neurocysticercosis (NCC) during and after treatment with long-term follow-up.
Measured over Ongoing
Cysticercosis
Neurocysticercosis
1 sites across 1 states
Maryland1
  • Elise M O'Connell, M.D. · PRINCIPAL_INVESTIGATOR · National Institute of Allergy and Infectious Diseases (NIAID)

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  • The primary objective is to characterize the biochemical and clinical course of neurocysticercosis (NCC) during and after treatment with long-term follow-up.Ongoing

    To study the clinical course of cysticercosis following therapy and diminish morbidity associated with treatment of cysticercosis including neurocysticercosis or the inflammation associated with therapy