This observational study is looking at people with filarial infections (diseases caused by parasitic worms) to better understand how their bodies respond to the infection and to treatment. These infections can cause various health problems, from swelling to eye inflammation. Researchers will study your immune system and how it reacts to the infection and to treatment with Diethylcarbamazine, a standard medication for these conditions. The goal is to understand what makes some people more likely to get these infections, how the disease develops, and how well people respond to treatment. You can join if you are between 3 and 100 years old, have a filarial infection, and have access to a doctor outside of NIH. The study aims to enroll 500 participants, but the current recruitment status is unclear.

Study design

This is an observational study, meaning researchers will closely watch and study participants with filarial infections. It aims to enroll 500 participants.

What's involved

You will undergo routine clinical evaluations, and your blood cells and/or serum will be collected for laboratory studies. Your clinical and immune responses to therapy will be carefully observed, with long-term follow-up.

Compensation

Not stated in the trial record.

Follow-up

Your clinical and immunologic responses to therapy will be followed long-term, with primary endpoints measured at 10 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.