This study is looking at rare conditions like Proteus syndrome and related overgrowth disorders. Researchers want to understand what causes these conditions, how they change over time, and how they affect patients. Proteus syndrome causes overgrowth, benign (non-cancerous) tumors, and uneven limb growth. You might be able to join if you have Proteus syndrome or a specific genetic change called AKT1 p.Glu17Lys. The study aims to better understand these disorders at a molecular level (how they work in your body's cells) and track how symptoms develop. This is an observational study, meaning no specific interventions are being tested, and the status is currently unclear.

Study design

This is an observational study planning to include up to 1500 participants, ranging from 1 month to 99 years old.

What's involved

You would have a medical history review, physical exam, X-rays, and possibly other imaging tests like CT, MRI, and ultrasound. There will also be ongoing clinical assessments and follow-up.

Compensation

Not stated in the trial record.

Follow-up

The study involves ongoing follow-up to determine the natural history of the disorders.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.