Study of New Magnetic Resonance Imaging Methods of the Brain
This study aims to improve magnetic resonance imaging (MRI) techniques and equipment for studying brain function. MRI is a tool that provides information about brain chemistry and how it works. Researchers want to develop better ways to monitor blood flow in different brain areas when you do simple tasks. The MRI machine used in this study is more powerful than those typically found in hospitals, allowing for clearer, more detailed images. This study is looking for healthy volunteers aged 18 and older. You would have a medical history review, a questionnaire, and a neurological exam to see if you can join. If eligible, you would have an MRI scan once a year.
- Study design
- This is an observational study designed to develop and evaluate new MRI technology. It plans to enroll 1100 healthy volunteers.
- What's involved
- You would undergo a neurological physical exam, answer a health questionnaire, and have a yearly MRI scan.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your brain will be measured annually to evaluate the new MRI methods.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Study of New Magnetic Resonance Imaging Methods of the Brain
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Alan P Koretsky, Ph.D. · PRINCIPAL_INVESTIGATOR · National Institute of Neurological Disorders and Stroke (NINDS)
Who to contact
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Do you actually qualify for this trial?
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Inclusion
What this trial measures
- The purpose of this study is to develop and evaluate new MR pulse sequences and hardware for performing anatomical and functional MRI in the CNS at, 3.0T, and 7T with a high spatial resolution.annually
The primary outcome of this study will be the ability to robustly acquire whole brain MRI sensitized to myelin, iron, diffusion, perfusion, and fiber orientation. Perfusion- and BOLD- based fMRI techniques will allow distinguishing between neuronal and systemic vascular signal contributions. In addition, we anticipate the ability to acquire (proton) spectroscopic data at 5mm resolution.