Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

This observational study aims to find better ways to detect and prevent ovarian cancer early, especially for women at high risk. Researchers are collecting blood samples (to test for biomarkers like CA-125), tissue, and other body fluids to develop new markers for early detection. They are also using questionnaires to understand the quality of life for women at increased risk or diagnosed with ovarian cancer. You may be eligible if you are a woman between 18 and 80 years old and have a higher risk of ovarian cancer, such as having close relatives with ovarian, primary peritoneal, or fallopian tube cancer. The main goal is to develop better ultrasound and blood tests for ovarian cancer detection and management, with results measured at 1 year. The current status of this study is unclear.

Study design
This is an observational study with a planned enrollment of 6000 women. It is not specified if it is randomized or blinded.
What's involved
Participants will provide periodic specimens (blood, tissue, or body fluids) and data. They may also complete questionnaires about their psychological functioning.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints for developing detection methods are measured at 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT00005095

Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

Recruiting
Not specifiedAges 18–80Observational
Northwestern University
~6,000 participants
Updated 2025-02-28 on ClinicalTrials.gov
What's tested:Ca-125screening questionnaire administrationSurgery

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The development of ultrasound and serum tumor markers for the detection and management of ovarian cancer and other
Measured over 1 year
Cervical Cancer
Endometrial Cancer
Fallopian Tube Cancer
Hereditary Breast/Ovarian Cancer (brca1, brca2)
Ovarian Cancer
Sarcoma
Uterine Leiomyomata
Vaginal Cancer
Vulvar Cancer
1 sites across 1 states
Illinois1
  • Lee P. Shulman, MD · STUDY_CHAIR · Robert H. Lurie Cancer Center

Opens a ready-to-send draft in your own email app — review before sending.

  • The development of ultrasound and serum tumor markers for the detection and management of ovarian cancer and other1 year

    To identify markers to allow for presymptomatic testing for ovarian and other gynecological malignancies