This observational study aims to understand the different types of proteins found in the lungs of patients with pneumonia. Pneumonia causes lung inflammation, often due to an infection, and while X-rays can diagnose it, they don't always reveal the cause. Researchers hope to find specific proteins (biomarkers) that are linked to different forms of pneumonia, which could help guide treatment in the future. The study will analyze fluid collected during a standard procedure called a bronchoscopy (a procedure where a thin tube is inserted into the airways to look at the lungs and collect samples). This study is open to patients aged 3 to 99 years who are undergoing a diagnostic bronchoscopy at the NIH Clinical Center. The goal is to identify peptide biomarkers and characterize lung cells associated with pneumonia.

Study design

This is an observational study with a planned enrollment of 750 participants. It will involve collecting and analyzing samples from patients.

What's involved

You would participate if you are already undergoing a diagnostic bronchoscopy. Researchers will collect and analyze fluid from your lungs (BAL fluid) and review your medical records.

Compensation

Not stated in the trial record.

Follow-up

The study measures peptide biomarkers and characterizes lung cells at the time of batch-driven analysis of samples.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.