This observational study aims to understand the genetic factors that contribute to the development of lymphomas (cancers of the lymphatic system) and chronic lymphocytic leukemia (CLL). Researchers are collecting information from families where multiple members have these conditions. The goal is to identify unique genetic characteristics in familial lymphomas and potentially find a gene that increases the risk of developing lymphoma. You may be able to join if you are 18 or older, have been diagnosed with non-Hodgkin's lymphoma, Hodgkin's disease, or CLL, and have a first-degree relative (parent, sibling, or child) with a lymphoproliferative disorder (a condition where too many white blood cells called lymphocytes are produced). The study is currently unclear on its recruitment status and plans to enroll 1500 participants.

Study design

This is an observational study with a planned enrollment of 1500 participants. It is not testing a specific intervention or drug.

What's involved

You will be asked to complete detailed family and medical history questionnaires initially, with a follow-up questionnaire every year. You will also be asked to supply a blood sample and possibly a mouthwash sample, which can be done by mail, and consent to release your lymphoma tissue block.

Compensation

Not stated in the trial record.

Follow-up

Genetic factors will be measured indefinitely.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.