Observational Study of Head and Neck Tumor Genetics

This study aims to understand the genetic makeup of head and neck tumors and how it relates to how well treatments work and your long-term outcome. Researchers will look at tumor tissue from people with head and neck tumors, both cancerous and non-cancerous. They are trying to find patterns in your genes that can predict how you will respond to treatment and your chances of recurrence (the cancer coming back) and survival over 5 years. This is an observational study, meaning no specific treatments are being tested as part of the study itself. The study is looking to enroll about 1000 participants. The current recruitment status is unclear.

Study design
This is an observational study with a planned enrollment of 1000 participants. It is not testing a specific drug or intervention.
What's involved
You would need to have actual or suspected head and neck tumors and either be planning a biopsy or surgery, or have existing tumor tissue available.
Compensation
Not stated in the trial record.
Follow-up
The study will look at your treatment response and prognosis, including time to recurrence and survival, for up to 5 years.

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NCT00200486

Molecular and Genomic Profiling of Head and Neck Tumors

Recruiting
Not specifiedAll AgesObservational
Montefiore Medical Center
~1,000 participants
Updated 2026-04-09 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
correlation of treatment response and prognosis (time to recurrence and survival) with genetic expression profile
Measured over 5 years
Head and Neck Neoplasms
1 sites across 1 states
New York1
  • Richard V Smith, MD · PRINCIPAL_INVESTIGATOR · Montefiore Medical Center

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

actual or suspected malignant or non-malignant tumors of the head and neck
planned biopsy and/or resection, or availability of paraffin embedded or stored frozen tumor tissue for non-genetic analysis

Exclusion

insufficient tissue available for both standard diagnostic evaluation and study specimen
  • correlation of treatment response and prognosis (time to recurrence and survival) with genetic expression profile5 years