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Retinal Imaging in Inherited Retinal Degenerations

This study is looking at how to better understand inherited retinal degenerations, like Retinitis Pigmentosa, which cause vision loss. Researchers are using a special camera called an Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO) to take very detailed pictures of the retina (the light-sensing tissue at the back of your eye). They want to see if this camera can help them understand how these diseases affect vision. You might be able to join if you are at least 13 years old, speak English, and can travel to UC Berkeley. The study aims to measure cone spacing (the distance between light-sensing cells) after 24 months to see how the disease progresses. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will observe participants without providing an intervention. The study plans to enroll up to 400 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for at least 24 months to measure cone spacing.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT00254605

Retinal Imaging in Patients With Inherited Retinal Degenerations

Recruiting
Not specifiedAges 13+Observational
University of California, San Francisco
~400 participants
Updated 2026-06-05 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cone spacing
Measured over 24 months

Conditions

Retinitis Pigmentosa

Explore related trials

Retinitis Pigmentosa

NCT00254605

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Department of Ophthalmology Retinal Degenerations Clinic, UCSF

    San Francisco, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Jacque L. Duncan, M.D. · PRINCIPAL_INVESTIGATOR · University of California, San Francisco

Who to contact

Jacque L. Duncan, M.D.
[email protected]
415-514-4241
Email the study team

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Eligibility criteria

Inclusion

Subjects must speak and understand English
Subjects must have pupils that dilate to at least 6 millimeters diameter.
Subjects must be willing to travel to University of California (UC) Berkeley.
Subjects are financially responsible for their travel to the San Francisco area if they are not San Francisco residents.

Exclusion

Cataract
Irregular corneal astigmatism (keratoconus)
Prior refractive surgery

What this trial measures

  • Cone spacing24 months

    The current study will assess cone spacing twice at baseline and every 6 months for 30 months. The primary outcome will be measured at 24 months.