Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF) Study

This observational study is looking for specific genetic traits that might explain why people develop pulmonary fibrosis (scarring of the lungs) and how these traits affect the patterns of inflammation and scarring in the lungs. Researchers are collecting samples to understand the molecular causes of Idiopathic Pulmonary Fibrosis (IPF), a severe lung disease. You may be able to join if you are 18 or older, have a confirmed diagnosis of pulmonary fibrosis, and are seeking treatment at the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease. The study aims to collect samples for up to 5 years to identify these genetic factors. This study does not involve any specific interventions or treatments.

Study design
This is an observational study aiming to enroll 2000 participants. It is not testing a specific drug or treatment.
What's involved
Sample collection will occur, and this process may continue for up to 5 years. The record does not specify the frequency or type of visits or procedures.
Compensation
Not stated in the trial record.
Follow-up
Sample collection will occur up to 5 years. The record does not specify follow-up after sample collection.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT00258570

Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)

Recruiting
Not specifiedAges 18+Observational
University of Pittsburgh
~2,000 participants
Updated 2025-11-12 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)
Measured over Sample collection will occur up to 5 years based on the current rate of sample collection.
Pulmonary Fibrosis
1 sites across 1 states
Pennsylvania1
  • Kevin F Gibson, MD · PRINCIPAL_INVESTIGATOR · University of Pittsburgh, Simmons Center for ILD

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

18 years of age or older
Diagnosis of pulmonary fibrosis confirmed by physical examination, pulmonary function testing, chest X-ray, and computed tomography (CT) scans.
Adult patients who are seeking treatment at the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease.

Exclusion

Under 18 years of age
Non-fibrotic ILD
  • Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)Sample collection will occur up to 5 years based on the current rate of sample collection.

    Blood samples will be collected to validate in a large cohort the per- allele associations of prespecified SNPs with IPF case status adjusted for age , sex. smoking, and principal components of ancestry.