This study is looking at whether pyridostigmine, a medication, can help people with Postural Tachycardia Syndrome (POTS). POTS is a condition where your heart rate increases significantly when you stand up, causing symptoms like lightheadedness and weakness. Researchers expect pyridostigmine to improve heart rate and blood pressure. You could be eligible if you are between 15 and 55 years old and have a POTS diagnosis, confirmed by a specific heart rate increase when standing and experiencing orthostatic symptoms. The study will measure changes in your symptoms after 3 days to see if pyridostigmine is effective. The current recruitment status is unclear.

Study design

This is an interventional study with 50 planned participants. It is a blinded study, meaning neither you nor the study doctor will know if you are receiving pyridostigmine or a placebo (an inactive substance).

What's involved

You would have two visits to the clinic. The first visit takes about 3 hours, and the second visit, two days later, takes about 2 hours. You would take one capsule daily for 3 days.

Compensation

Not stated in the trial record.

Follow-up

Your symptoms will be measured at 3 days after starting the medication.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.