Psychophysical Studies of Cancer Therapy Pain

This observational study is looking at how cancer treatment affects pain, specifically neuropathic pain (nerve pain) that can develop after chemotherapy. Researchers want to see if special sensory tests, called quantitative sensory testing, can help understand the properties of this pain. These tests measure your sensitivity to things like touch, heat, cold, and pinpricks. The study will also look at whether nerve damage in the skin is related to the pain. You might be tested before starting chemotherapy or if you're already experiencing nerve pain from treatment. The goal is to better understand and characterize this type of pain in people with advanced cancer. This study is for adults aged 18 and older who can understand and consent to participate. The study aims to enroll 450 participants.

Study design
This is an observational study, meaning researchers will observe and collect information without giving any specific intervention beyond the sensory tests. It aims to enroll 450 participants.
What's involved
You will participate in sensory tests that take about 1 hour. These tests involve measuring your sensitivity to different stimuli like touch, heat, cold, and pinpricks. You may be tested multiple times throughout your chemotherapy or at later follow-up appointments.
Compensation
Not stated in the trial record.
Follow-up
You may be tested at repeated intervals throughout your chemotherapy or at later follow-up dates to check the length of symptoms.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT00515060

Psychophysical Studies of Cancer Therapy Pain

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~450 participants
Updated 2026-06-10 on ClinicalTrials.gov
What's tested:Sensory Tests

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Participant Heat + Cold Pain Threshold
Measured over 1 Hour Sensory Testing: Baseline + testing at repeated intervals throughout chemotherapy or at later follow-ups.
+1 more outcome measured
Advanced Cancer
Pain
1 sites across 1 states
Texas1
  • Patrick M. Dougherty, PhD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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  • Participant Heat + Cold Pain Threshold1 Hour Sensory Testing: Baseline + testing at repeated intervals throughout chemotherapy or at later follow-ups.
  • Participant Mechanical Testing Results <Touch Detection Threshold; Sharpness Threshold + Pain Ratings to Needle Probe; Bump Test>1 Hour Sensory Testing: Baseline + testing at repeated intervals throughout chemotherapy or at later follow-ups.