Observational Study on Risk Factors for Primary Graft Dysfunction After Lung Transplant
This observational study is looking at risk factors for Primary Graft Dysfunction (PGD), a serious complication that can happen after a lung transplant. Researchers want to see if high levels of certain chemicals in your blood, particularly those involved in bleeding and clotting (like protein C) or markers of oxidant stress (which can damage cells), might increase your chance of developing PGD. You could be eligible if you are between 13 and 68 years old and are having a lung or combined heart and lung transplant. The study aims to understand if these chemical levels are linked to PGD, which is measured within 72 hours after transplantation. The study status is unclear, and it plans to enroll 1150 participants.
- Study design
- This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to include 1150 participants.
- What's involved
- You would have blood samples collected before, immediately after, and 24 hours after your surgery. Researchers will also review your medical records.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome, Primary Graft Dysfunction, is measured within 72 hours following transplantation.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jason D. Christie, MD · PRINCIPAL_INVESTIGATOR · University of Pennsylvania
Who to contact
Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Primary graft dysfunction, defined by the ISHLT criteriaMeasured within 72 hours following transplantation