Pilot Study for Allergic Airway Inflammation in Asthma
This study is looking for people aged 18 to 50 with allergic asthma to better understand what causes inflammation in their airways. You might be able to join if you have asthma, a history of allergic symptoms to cat or dust mite, and a positive skin prick test to these allergens. The study involves a procedure called Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage. This procedure involves looking into your airways with a thin tube (bronchoscopy) and collecting fluid from your lungs after a small amount of cat or mite allergen is introduced. Researchers will then measure airway inflammation at 1, 6, or 24 hours to see how your body reacts. The goal is to identify factors that bring inflammatory cells to the airways in people with asthma. The current status of this study is unclear, and it plans to enroll 313 participants.
- Study design
- This is an interventional study, meaning participants will receive a specific procedure. It plans to enroll 313 participants.
- What's involved
- You would undergo Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage, with measurements taken at 1, 6, or 24 hours.
- Compensation
- Not stated in the trial record.
- Follow-up
- Airway inflammation will be measured at 1, 6, or 24 hours after the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Benjamin D Medoff, MD, PhD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital
Who to contact
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What this trial measures
- airway inflammation1,6, or 24 hours