Observational Study of Systemic Lupus Erythematosus in Gullah Health

This study is looking at Systemic Lupus Erythematosus (SLE), an autoimmune disease where your body's immune system attacks its own tissues. Researchers want to understand why African Americans are more likely to get SLE and often have more severe cases. They believe specific genetic factors, combined with environmental exposures, play a role. This study is focusing on the Gullah population from the Sea Islands of South Carolina and Georgia because their unique genetic background can help researchers explore these connections. You may be able to join if you are African-American Gullah, aged 2 or older, and either have SLE, are a relative of someone with SLE, or are a healthy Gullah control. The study aims to enroll 750 participants. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will observe and collect information without providing any specific treatments. It aims to include 750 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

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NCT00756769

Systemic Lupus Erythematosus in Gullah Health

Recruiting
Not specifiedAges 2+Observational
Medical University of South Carolina
~750 participants
Updated 2026-07-28 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring

A primary outcome measure isn't published for this study.

Systemic Lupus Erythematosus
1 sites across 1 states
South Carolina1
  • Diane L. Kamen, MD, MSCR · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina

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Eligibility criteria

Inclusion

Age 2 years and above;
Self-identified as African-American "Gullah" from the Sea Island region of South Carolina;
Have had at least 4 of the 11 diagnostic criteria for SLE as designated by the American College of Rheumatology (ACR), be a relative of a known SLE patient, or be an unrelated healthy Gullah control;
Ability to speak and understand English;
Ability and willingness to give informed consent

Exclusion

Race defined by participant as other than Black or African-American;
Being a prisoner, mentally ill patient, or institutionalized individual;
Unwilling or unable to give informed consent