Lifetime Study of Childhood Cancer Survivors

This observational study, called SJLIFE, aims to understand the long-term health of adults who survived childhood cancer treated at St. Jude Children's Research Hospital. Many health risks from childhood cancer treatment might not appear until years later. This study will follow 10,000 survivors to track their health outcomes as they age. You may be able to join if you were treated or followed at St. Jude for a childhood cancer, are at least five years past your diagnosis, and are willing to participate. The goal is to create a group of survivors that researchers can study over their lifetimes to learn more about these health effects.

Study design
This is an observational study planning to enroll 10,000 participants. It is being implemented in stages, including surveys and pilot studies, before establishing a prospective lifetime cohort.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed until they withdraw, are taken off the study, or die, up to December 2025 and potentially for up to 20 years.

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NCT00760656

Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer

Recruiting
Not specifiedAges 5+Observational
St. Jude Children's Research Hospital
~10,000 participants
Updated 2026-06-17 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To establish a lifetime cohort of childhood cancer survivors treated at St. Jude Children's Research Hospital to facilitate evaluation of health outcomes in aging children and adults surviving pediatric cancer.
Measured over Until the last participant withdraws, is taken off study, or dies (up until December 2025) up to 20 years
Cancer
1 sites across 1 states
Tennessee1
  • Melissa Hudson, MD · PRINCIPAL_INVESTIGATOR · St. Jude Children's Research Hospital

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Eligibility criteria

Inclusion

Patient will have a diagnosis of childhood malignancy (or neoplasm requiring similar therapy) that was treated or followed at St. Jude Children's Research Hospital.
Patient will be at least five years from diagnosis.
Patient is willing to participate at any level of study
Patient is willing to comply with the guidelines of St. Jude domiciliary care facilities
Patient or legally authorized representative must sign informed consent for study participation.
≥5 years of age
Non-first degree relatives or friends of St. Jude patients or former patients or SJCRH employees/affiliates who are not SJLIFE study team members, or family members of SJLIFE study team, or supervised by a SJLIFE study team members, or any volunteer not associated with St. Jude.
Participant does not have a diagnosis of childhood malignancy or childhood neoplasm requiring similar therapy (i.e., diagnosed \<21 years of age).
Participant is not currently pregnant or lactating.
Patient is willing to comply with the guidelines of St. Jude domiciliary care facilities.
Patient must sign informed consent for study participation.
Enrolled participant in the SJLIFE study.
At-risk for long lasting difficulties with walking or other aspects of mobility.
Participant is not currently pregnant.
Participant or their designee signs informed consent for Gait and Mobility Lab Assessment participation.

Exclusion

Patient or control subject refuses to participate at any level of study
Prospective participant or their designee declines participation in the Gait and Mobility Lab Assessment.
  • To establish a lifetime cohort of childhood cancer survivors treated at St. Jude Children's Research Hospital to facilitate evaluation of health outcomes in aging children and adults surviving pediatric cancer.Until the last participant withdraws, is taken off study, or dies (up until December 2025) up to 20 years