Understanding Impaired Diabetic Wound Healing

This observational study aims to understand why wounds heal poorly in people with diabetes. Researchers will collect blood and a VAC sponge (a material normally thrown away after wound care) from people with chronic (long-lasting) wounds. They will compare cells and fluids from diabetic and non-diabetic wounds, as well as normal blood cells, to find out what causes problems with healing. You may be able to join if you are between 21 and 80 years old and have a chronic wound that has been present for over four weeks, whether you have diabetes or not. The study will look at how well wounds heal after 16 weeks. The current recruitment status is unclear.

Study design
This is an observational study planning to enroll 250 participants. It is designed to understand the differences in wound healing between diabetic and non-diabetic individuals.
What's involved
You would have blood drawn once, and a VAC sponge would be collected. This sponge is material that is usually discarded during standard wound care.
Compensation
Not stated in the trial record.
Follow-up
Wound healing will be measured at Week 16.

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NCT00777712

Mechanisms Underlying Impaired Diabetic Wound Healing

Recruiting
Not specifiedAges 21–80Observational
University of Pittsburgh
~250 participants
Updated 2026-06-05 on ClinicalTrials.gov
What's tested:Blood draw

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Wound healing
Measured over Week 16
Non-healing Wound
2 sites across 1 states
Pennsylvania2
  • Sashwati Roy, Ph.D. · PRINCIPAL_INVESTIGATOR · University of Pittsburgh

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Eligibility criteria

Inclusion

Ages 21-80
Chronic Wound (present \>4 weeks)
Diabetic \& Non-diabetic
Adult surgical wounds

Exclusion

Inability to consent
Pregnant women
Therapeutically immunocompromised
Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9
  • Wound healingWeek 16

    Wound healing status