Observational Study of Angiogenesis in Skin Diseases

This study is looking at how a process called angiogenesis (the formation of new blood vessels) plays a role in various skin diseases like port wine stains, rosacea, and psoriasis. Researchers believe that in many skin conditions, there's an increase in factors that promote new blood vessel growth. To understand this better, they will analyze skin tissue samples, either new ones or those already collected. These samples will be checked for markers related to angiogenesis. Some samples may also undergo genetic testing to explore the underlying molecular reasons for these changes. The goal is to identify factors in these skin diseases. You can participate if you are 16 years or older and are willing to have a skin biopsy. The study aims to include 85 participants, but its current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will collect and analyze existing or newly collected skin tissue samples. It is not a treatment study.
What's involved
You would need to be willing to have a skin biopsy. Researchers may also use discarded skin tissue from surgical or biopsy procedures.
Compensation
Not stated in the trial record.
Follow-up
Factors in dermatologic diseases will be measured for up to 4 weeks.

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NCT00842283

Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target

Recruiting
Not specifiedAges 16+Observational
University of California, Irvine
~85 participants
Updated 2026-04-13 on ClinicalTrials.gov
What's tested:skin tissue sample

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Factors in dermatologic diseases.
Measured over up to 4 weeks
Dermatologic Diseases
2 sites across 1 states
California2
  • Kristen Kelly, MD · PRINCIPAL_INVESTIGATOR · University of California, Irvine

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Eligibility criteria

Inclusion

16 years of age or older.
willing to have a skin biopsy

Exclusion

under 16 years of age
unable to carry out instructions
  • Factors in dermatologic diseases.up to 4 weeks

    Evaluate the role of angiogenesis in cutaneous disease and ultimately, facilitate implementation of anti-angiogenic therapy in a wide range of dermatologic diseases including port wine stains, hemangiomas, angiofibromas, Kaposi's sarcoma, angiosarcoma, scars, rosacea and psoriasis.