An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Ashesh Mehta, M.D., Ph.D. · PRINCIPAL_INVESTIGATOR · Zucker School of Medicine at Hofstra/Northwell and Feinstein Institute for Medical Research
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
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What this trial measures
- Decrease in seizure frequency after epilepsy surgical treatmentup to 4 weeks
We are interested in identifying specific factors that predict the effects of epilepsy surgery on seizure control. We will start by assessing electrographic (seizure foci and spread), imaging (cortical volume, presence of structural pathology), and surgical (extent of surgical resection) factors.
- Change in electrophysiological markers (local field potential power and phase) during cognitive tasksup to 4 weeks
We will compare brain recordings during distinct cognitive functional states, as defined by performance and participation in cognitive tasks (typically task vs resting state). Power and phase measures isolated from local field potentials in implanted electrodes will be assessed. Neuronal firing rates will also be assessed.
- Change in memory performanceup to 4 weeks
We will measure the change in memory performance in memory tasks (percent of items correctly recalled).
- Change in decision-making performanceup to 4 weeks
We will measure the change in performance (reaction time and accuracy) in decision-making tasks.
- Change in sensory perceptionup to 4 weeks
We will measure the change in performance in auditory/visual perception tasks (percent of items correctly perceived).