This observational study is looking for new ways to identify people at higher risk for gastrointestinal (GI) cancers like colorectal, esophageal, gastric, and pancreatic cancer. Researchers are collecting tissue samples and body fluids (like blood, urine, or stool) from people who are having a colonoscopy, endoscopy, or surgery. They want to find 'biomarkers' – substances in these samples that could signal cancer risk. The goal is to develop better screening methods. You might be able to join if you are 18 or older, are having a colonoscopy or endoscopy at Vanderbilt or the VA Medical Center, and have a diagnosis or history of GI cancer, polyps, or inflammatory bowel disease.

Study design

This is an observational study involving up to 5000 participants. It is not testing a specific drug or treatment.

What's involved

You would provide tissue and biofluid samples during your colonoscopy, endoscopy, or surgery. Information from your medical record will also be collected.

Compensation

Not stated in the trial record.

Follow-up

Participants are followed once a year for up to 5 years to see if biomarkers have a prognostic significance.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.