Cervical Cancer Detection Using Optical Spectroscopy

This study is exploring new ways to detect cervical cancer using special light-based devices. Researchers are testing two devices: an Optical Spectroscopy Bench-Top System and a Portable Optical Spectrometer, along with a Transvaginal colposcope (a magnifying device used to examine the cervix). The goal is to find unique "optical signatures" in cervical tissue that could indicate dysplasia (abnormal cell growth that can lead to cancer). You may be able to join if you are a woman aged 18 or older who is having a colposcopy for cervical cancer diagnosis, undergoing LEEP (Loop Electrosurgical Excision Procedure) for early-stage cervical cancer, or having a follow-up Pap smear. The study's current status is unclear.

Study design
This interventional study plans to enroll 350 women. It is not specified if it is randomized or blinded.
What's involved
The primary measurement, identifying optical signatures, takes less than 10 minutes on the day of the procedure.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

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NCT00900575

Cervical Cancer Detection Using Optical Spectroscopy

Recruiting
NAAges 18+InterventionalDiagnostic
Duke University
~350 participants
Updated 2026-03-06 on ClinicalTrials.gov
What's tested:Optical Spectroscopy Bench-Top SystemPortable Optical SpectrometerTransvaginal colposcope

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Identification of optical signatures of cervical tissue
Measured over Day of procedure (less than 10 minutes)
Cervical Cancer
1 sites across 1 states
North Carolina1
  • Nimmi Ramanujam, Ph.D. · PRINCIPAL_INVESTIGATOR · Duke University

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Eligibility criteria

Inclusion

undergoing colposcopy for the diagnosis of cervical cancer
LEEP for the treatment of cervical cancer in early stages.
Follow-up Pap smear in surveillance

Exclusion

Women under the age of 18 (minors) will be excluded from this study.
patients will be excluded if she has had a recent episode of bleeding or preterm labor.
Subjects who are not competent to give consent will excluded
  • Identification of optical signatures of cervical tissueDay of procedure (less than 10 minutes)

    The primary outcome of this study is the identification of the optical signatures of cervical tissue.