Electro-Acupuncture for High Blood Pressure

This study is investigating if electro-acupuncture (EA) can help lower high blood pressure (hypertension). Researchers believe EA might work by calming the sympathetic nervous system, which plays a role in blood pressure regulation. You could be eligible if you are between 18 and 85 years old, have high blood pressure (with or without medication), and have mild coronary disease without significant heart rhythm changes on an ECG (electrocardiogram). The study will measure your blood pressure after 8 weeks to see if EA has a positive effect. The current status of this study is unclear, and it aims to enroll 160 participants.

Study design
This interventional study plans to enroll 160 participants. It compares two types of electro-acupuncture, electro-acupuncture control and electro-acupuncture test.
What's involved
You would have an initial visit for blood pressure monitoring for 60 minutes, followed by 24 hours of monitoring. This would be followed by 6-8 visits for 30-minute electro-acupuncture treatments.
Compensation
Not stated in the trial record.
Follow-up
Blood pressure will be measured at 8 weeks to assess the primary outcome.

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NCT00932139

Effect of Electro-Acupuncture on Blood Pressure

Recruiting
NAAges 18–85InterventionalTreatment
University of California, Irvine
~160 participants
Updated 2025-04-15 on ClinicalTrials.gov
What's tested:Electro-acupuncture controlElectro-acupuncture test

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
blood pressure
Measured over 8 weeks
Hypertension
2 sites across 1 states
California2
  • Shaista Malik, MD, PhD, MPH · PRINCIPAL_INVESTIGATOR · University of California, Irvine
  • Liang-Wu Fu, MD, PhD · PRINCIPAL_INVESTIGATOR · University of California, Irvine
  • LiFang Xie, PhD, LAc · PRINCIPAL_INVESTIGATOR · University of California, Irvine

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Eligibility criteria

Inclusion

Patients with mild coronary disease, and no significant ECG change reflecting ischemia at rest.
Patients with high blood pressure with or without antihypertensive medication.

Exclusion

Pregnant or nursing women
Individuals with severe coronary disease (continuous angina)
Conduction abnormalities on ECG consistent with left bundle branch block
Cardiac arrhythmias associated with low blood pressure (90 mmHg)
Peripheral vascular disease
Orthopedic disease
Diabetic or psychological illness that could interfere with safe performance of exercise of psychophysiological stress testing
Those with known sensitivity to topical preparations or strong reactions to medical dressings and skin tapes
  • blood pressure8 weeks

    evaluation of systolic and diastolic blood pressures changes