Understanding Severe Viral Infections
This observational study aims to understand why some people get very sick from common viral infections like those caused by EBV, HSV, VZV, HPV, and CMV, even when they don't have known immune problems. Researchers want to find immune system weaknesses or genetic factors that make individuals more prone to severe or unusual viral infections. You may be able to join if you are between 2 and 100 years old and have a confirmed severe or unusual viral infection. This study is not testing any specific treatments or interventions. The goal is to identify these underlying causes over a 10-year period.
- Study design
- This is an observational study planning to enroll 600 participants. It is not testing a specific drug or intervention.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary goal is measured at 10 years, suggesting a long-term follow-up.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jessica R Durkee-Shock, M.D. · PRINCIPAL_INVESTIGATOR · National Institute of Allergy and Infectious Diseases (NIAID)
Who to contact
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What this trial measures
- To find immune and/or genetic defects that predispose individuals to severe or unusual viral infections.10 years
Patients under immune and genetic testing.