Breast Cancer Proteomics and Radiomics Research

This research study is looking for people aged 18 or older who are having surgery for breast nodules (lumps), breast tissue reduction, preventive mastectomy, or have recently been diagnosed with invasive breast cancer. The goal is to collect fresh breast tissue samples from both cancerous and non-cancerous areas. Researchers will then study the fluid within these tissues to find unique patterns (profiles) that can help tell the difference between breast cancer and non-cancerous conditions. This information could lead to new blood tests for diagnosing breast cancer and predicting how it might progress. The study is currently observational, meaning it involves collecting information without giving any specific treatments, and its recruitment status is unclear.

Study design
This is an observational case-control study planning to enroll 300 participants. It compares tissue samples from different breast conditions.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

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NCT01042548

Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum

Recruiting
Not specifiedAges 18+Observational
University of Pittsburgh
~300 participants
Updated 2026-05-07 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring

A primary outcome measure isn't published for this study.

Breast Cancer
1 sites across 1 states
Pennsylvania1

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Eligibility criteria

Inclusion

All subjects ≥ 18 years of age undergoing surgery for indeterminate breast nodules, breast tissue reduction, prophylactic mastectomy, and all subjects with newly diagnosed invasive breast cancer will be eligible to participate. If invasive breast cancer or suspicion of invasive breast cancer, target lesion must measure ≥ 1.0 cm on breast imaging before core biopsy.

Exclusion

Anyone \< 18 years of age.
Multiple synchronous primary malignancies from different organ systems.