Understanding Attention and Visual Processing in Brain Lesions

This observational study aims to better understand how different parts of the brain help us pay attention to what we see. Researchers are comparing people who have had damage to specific parts of their brain (like from a stroke or injury) with healthy volunteers. They want to see how these groups process visual information and how attention affects this process. The study will involve behavioral tasks and MRI scans to look at brain activity. The main goal is to identify which brain areas, particularly in the front and top-back parts of the brain, are involved in controlling our attention and how they influence what we see. This study does not test any specific drugs or interventions.

Study design
This is an observational study planning to enroll 300 participants. It compares individuals with focal brain lesions to healthy volunteers.
What's involved
You would have 4 to 10 visits to the NIH Clinical Center over 1 to 2 years. Each visit is expected to last about 2 hours.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, MRI signal, is measured at an ongoing basis, but the duration of follow-up is not specified beyond the 1-2 year study period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT01087281

Top-Down Attentional Control of Visual-Processing

Recruiting
Not specifiedAges 18+Observational
National Institute of Mental Health (NIMH)
~300 participants
Updated 2026-08-24 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
MRI signal across the whole brain during the MRI scans
Measured over Ongoing
Focal Brain Lesion
Focal Lesions
fMRI
1 sites across 1 states
Maryland1
  • Shruti A Japee, Ph.D. · PRINCIPAL_INVESTIGATOR · National Institute of Mental Health (NIMH)

Opens a ready-to-send draft in your own email app — review before sending.

  • MRI signal across the whole brain during the MRI scansOngoing

    The MRI signal varies with cortical area and with the stimuli and tasks performed by the subjects.