Back to search results

VRC 900: Understanding Immune Responses to Vaccines and Infections

This observational study, VRC 900, aims to better understand how your immune system (the body's defense against illness) responds to vaccines and natural infections. Researchers will collect blood, body fluids, and tissue samples from adults aged 18 and older. The goal is to learn more about what makes an immune response protective, which can help in developing new vaccines and treatments for infectious diseases. This study is currently unclear on its recruitment status and plans to enroll up to 500 participants. There are no specific interventions or drugs being tested; instead, the focus is on analyzing your body's natural immune reactions.

Study design
This is an observational study designed to collect specimens and data from up to 500 adult participants. It is not a randomized or blinded study.
What's involved
You would donate specimens for storage, which may include blood, body fluids, and tissue samples. Imaging using ultrasonography may also be used to guide sampling.
Compensation
Not stated in the trial record.
Follow-up
Immune responses will be measured throughout the study, but a specific follow-up duration is not mentioned.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT01132859

VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and Older

Recruiting
Not specifiedAges 18+Observational
National Institute of Allergy and Infectious Diseases (NIAID)
~500 participants
Updated 2026-09-01 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To use specimens and accumulated data for enhancement of understanding the correlates of immune protection.
Measured over Throughout the study
+2 more outcomes measured

Conditions

Immunity, Mucosal
Immune System Processes
Blood Specimen Collection

Explore related trials

Healthy Volunteer

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Lesia K Dropulic, M.D. · PRINCIPAL_INVESTIGATOR · National Institute of Allergy and Infectious Diseases (NIAID)

Who to contact

OPS Team, VRC
[email protected]
Not Listed
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

What this trial measures

  • To use specimens and accumulated data for enhancement of understanding the correlates of immune protection.Throughout the study

    By sample collection and imaging studies

  • To evaluate blood, body fluid, and tissue immune responses and pathogen dynamics of naturally infected and antigen-na(SqrRoot) ve subjectsThroughout the study

    By sample collection and imaging studies

  • To evaluate innate, humoral, and cellular immune responses and pathogen dynamics in the context of vaccination in the blood, body fluids, excretions, and tissuesThroughout the study

    By sample collection and imaging studies