Understanding Brain Development in Williams Syndrome

This observational study aims to understand how the brains of children with Williams syndrome and 7q11.23 duplication syndrome develop over time, compared to healthy children. Researchers are using functional magnetic resonance imaging (fMRI) to look at brain activity and changes. The goal is to learn more about how genetic differences affect brain development and function in these conditions. This study is looking for about 415 participants, including children with Williams syndrome, 7q11.23 duplication syndrome, or other 7q11.23 genetic variations, as well as healthy children, all aged 5 years and older. The study is currently ongoing.

Study design
This is an observational study, meaning participants will be studied without receiving any specific intervention. It plans to enroll about 415 participants.
What's involved
Participants will undergo fMRI task procedures. The duration of these procedures is ongoing.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT01132885

Defining the Brain Phenotype of Children With Williams Syndrome

Recruiting
Not specifiedAges 5+Observational
National Institute of Mental Health (NIMH)
~415 participants
Updated 2026-08-04 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
fMRI Task Procedures
Measured over Ongoing
Williams Syndrome
Duplication
1 sites across 1 states
Maryland1
  • Karen F Berman, M.D. · PRINCIPAL_INVESTIGATOR · National Institute of Mental Health (NIMH)

Opens a ready-to-send draft in your own email app — review before sending.

  • fMRI Task ProceduresOngoing

    fMRI Task Procedures