Observational Study on the Genetics of Congenital Heart Disease
This observational study aims to understand the genetic causes of Congenital Heart Disease (CHD), which are birth defects affecting the heart. While some genetic factors are known, the cause for most CHD cases is still a mystery. Researchers will collect blood samples from individuals with CHD or their family members. These samples will be analyzed using various genetic techniques, including whole genome sequencing, to identify new genes that contribute to CHD. The goal is to find these new genetic contributors within three years of starting the genetic analysis. This study is open to all ages and genders who have CHD or are related to someone with CHD.
- Study design
- This is an observational study planning to include up to 5000 participants. It is not a treatment study but rather focuses on understanding the genetics of Congenital Heart Disease.
- What's involved
- Participants will provide a blood sample for genetic analysis. The record does not specify any further visits or procedures.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, identification of novel genetic contributors, is measured at up to 3 years from the date of genetic analysis.
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Genetics of Congenital Heart Disease
At a glance
Conditions
NCT01192048
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Nationwide Children's Hospital
Columbus, Ohiono site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Vidu Garg, MD · PRINCIPAL_INVESTIGATOR · Nationwide Children's Hospital
Who to contact
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Inclusion
Exclusion
What this trial measures
- Identification of novel genetic contributors to congenital heart defectsup to 3 years, from date of genetic analysis to completion of genetic data analysis or identification of novel genetic contributors, whichever comes first
Novel genetic abnormalities that are found to be associated with congenital heart defects in humans