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NCT01244802

Characterization of Human Memory Immune Responses to Prior Yellow Fever Vaccination

Enrolling by Invitation
Not specifiedAges 18+Observational
Emory University
~300 participants
Updated 2024-11-04 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Determine the phenotypic and functional characterization of memory T cell responses to YF vaccination
Measured over Immune responses will be measured from at least 30 days after yellow fever vaccination.

Conditions

Yellow Fever Vaccine

Explore related trials

Administration of yellow fever vaccine

Where it's being run

1 sites across 1 states
Georgia1

Study leadership

  • Rafi Ahmed, PhD · STUDY_CHAIR · Emory University
  • Srilatha Edupuganti, MD · PRINCIPAL_INVESTIGATOR · Emory University

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Able to understand and give informed consent
Age 18-45 years (Group 1) or 55 years and above (Group 2) at the time of yellow fever vaccination
Documentation (international certificate of vaccination (yellow card) or medical record) indicating receipt of yellow fever vaccine.

Exclusion

Recipient of any vaccines within 30 days before the study visit (not applicable to older adults)
History of a progressive and severe chronic medical condition resulting in impaired immunity (such as diabetes, kidney or liver dysfunction)
Required use of immunosuppressive medications
Reporting HIV, Hepatitis B (surface antigen positive) or Hepatitis C infections (antibody positive) on the medical/health history form
Recipient of a blood product or immune globulin product within 42 days of study visit
Reporting pregnancy

What this trial measures

  • Determine the phenotypic and functional characterization of memory T cell responses to YF vaccinationImmune responses will be measured from at least 30 days after yellow fever vaccination.

    This is an exploratory analysis of variation in immune response with time since last yellow fever virus vaccination.