This observational study aims to understand how the brains of people with schizophrenia or schizoaffective disorder function differently compared to healthy individuals. Researchers will collect information like clinical interviews, behavioral data, blood samples, and brain scans (MRI and fMRI) from up to 1000 volunteers. The study is looking for participants aged 18 to 60 who have been diagnosed with schizophrenia or schizoaffective disorder, or healthy volunteers. You must be able to give informed consent, have corrected eyesight of 20/40 or better, and be able to read, speak, and understand English. The main goal is to see how brain activity in a specific area called the hippocampus differs between these groups while performing cognitive tasks. The study's current status is unclear.

Study design

This is an observational study planning to enroll up to 1000 participants. It is not testing a specific intervention or drug.

What's involved

You would undergo clinical interviews, behavioral task training, a medical check-up, and standard and functional MRI scans. Data collection will occur over 4-6 weeks until all study procedures are complete.

Compensation

Not stated in the trial record.

Follow-up

Participants will be assessed over the course of 4-6 weeks, until all study procedures are complete.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.