Understanding Sjogren's Disease

This study aims to better understand Sjogren's Disease, a condition that causes dry eyes and dry mouth, and can affect other parts of the body. Researchers want to learn how the disease starts and how it progresses in patients. There are no specific interventions or drugs being tested in this study. Instead, researchers will follow people with Sjogren's Disease and healthy individuals over time to collect information and samples. The goal is to identify potential markers (biomarkers) that could help in diagnosing and treating the disease in the future. You may be able to join if you are 16 years or older and have a diagnosis of Sjogren's Disease or at least two symptoms of the condition. The study plans to enroll up to 300 participants, but its current status is unclear.

Study design
This is an observational study, meaning participants will be followed over time without receiving any specific treatment from the study. It plans to enroll up to 300 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 10 years to collect clinical information and samples.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT01425892

The Pathogenesis and Natural History of Sjogren's Disease

Recruiting
Not specifiedAges 16+Observational
National Institute of Dental and Craniofacial Research (NIDCR)
~300 participants
Updated 2026-08-28 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Clinical phenotyping of SjD patients and controls over time Collection of samples for concurrent and future laboratory studies related to the pathogenesis Identification of biomarker candidates in SjD
Measured over patients are followed up to 10 years
Sjogren's Syndrome
Salivary Gland
Pathogenesis
1 sites across 1 states
Maryland1
  • Zohreh Khavandgar, D.D.S. · PRINCIPAL_INVESTIGATOR · National Institute of Dental and Craniofacial Research (NIDCR)

Opens a ready-to-send draft in your own email app — review before sending.

  • Clinical phenotyping of SjD patients and controls over time Collection of samples for concurrent and future laboratory studies related to the pathogenesis Identification of biomarker candidates in SjDpatients are followed up to 10 years

    following the natural history of Sjogren's disease progression.