NCT01451502

Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units

Recruiting
NAAll AgesInterventional
Masonic Cancer Center, University of Minnesota
~250 participants
Updated 2026-05-08 on ClinicalTrials.gov
What's tested:Umbilical Cord Blood (UCB)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of Blood Borne Pathogen Transmission from Unlicensed UCB Units.
Measured over Within 24 Hours Post Infusion
Lymphatic Diseases
Hematopoietic Malignancy
1 sites across 1 states
Minnesota1
  • Alex Hoover, MD, MSc · PRINCIPAL_INVESTIGATOR · Masonic Cancer Center, University of Minnesota

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Eligibility criteria

Inclusion

Subjects with any diagnosis for which there is an institutional review board (IRB) approved treatment protocol that requires UCB as a source of hematopoietic stem cells for lympho-hematopoietic reconstitution after myeloablative or non myeloablative conditioning.
Subject (or parent/guardian) must provide written informed consent for the use of unlicensed UCB units with co-enrollment onto a University of Minnesota IRB-approved clinical trial that details the disease specific treatment plan that prescribes the use of UCB as source of cells
Subject has an unlicensed UCB unit that meets required cell dose and HLA matching criteria (as defined in the primary treatment protocol) that is considered negative for tested blood-borne pathogens and also lack an 'equivalent', licensed UCB unit from a University of Minnesota approved Cord Blood Bank
  • Incidence of Blood Borne Pathogen Transmission from Unlicensed UCB Units.Within 24 Hours Post Infusion

    Documentation of events for the purpose of this study will only be for those events at least possibly related to the unlicensed UCB. Monitoring for acute infusional toxicities will end 24 hours after the umbilical cord blood (UCB) infusion.