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Transoral Robotic Surgery for Head and Neck Tumors

This study is looking at a type of surgery called transoral robotic surgery (TORS) for people with benign (non-cancerous) or malignant (cancerous) tumors in the head and neck area. TORS uses a robot to perform surgery through the mouth, which may lead to fewer side effects and a faster recovery compared to traditional surgery. The study wants to see if TORS is a practical and effective option for these types of tumors. You might be able to join if you are 18 or older and have certain head and neck tumors that can be reached through the mouth. The study will follow participants for up to eight years to see how well the surgery works.

Study design
This is a pilot single-arm study, meaning all 600 participants will receive the same intervention. The phase of the study is not specified.
What's involved
You would undergo transoral robotic surgery and have regular clinical assessments. You will also be asked to complete quality of life assessments.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to eight years after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT01473784

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Recruiting
NAAges 18+InterventionalTreatment
Ohio State University Comprehensive Cancer Center
~600 participants
Updated 2026-02-10 on ClinicalTrials.gov
What's tested:transoral robotic surgeryquality of life assessment

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Determine the feasibility of the TORS in patients with oral and laryngopharyngeal benign and malignant lesions.
Measured over up to eight years

Conditions

Recurrent Adenoid Cystic Carcinoma of the Oral Cavity
Recurrent Mucoepidermoid Carcinoma of the Oral Cavity
Recurrent Squamous Cell Carcinoma of the Hypopharynx
Recurrent Squamous Cell Carcinoma of the Larynx
Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity
Recurrent Verrucous Carcinoma of the Larynx
Recurrent Verrucous Carcinoma of the Oral Cavity
Stage 0 Hypopharyngeal Cancer
Stage 0 Laryngeal Cancer
Stage 0 Lip and Oral Cavity Cancer
Stage I Adenoid Cystic Carcinoma of the Oral Cavity
Stage I Mucoepidermoid Carcinoma of the Oral Cavity
Stage I Squamous Cell Carcinoma of the Hypopharynx
Stage I Squamous Cell Carcinoma of the Larynx
Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity
Stage I Verrucous Carcinoma of the Larynx
Stage I Verrucous Carcinoma of the Oral Cavity
Stage II Adenoid Cystic Carcinoma of the Oral Cavity
Stage II Mucoepidermoid Carcinoma of the Oral Cavity
Stage II Squamous Cell Carcinoma of the Hypopharynx
Stage II Squamous Cell Carcinoma of the Larynx
Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity
Stage II Verrucous Carcinoma of the Larynx
Stage II Verrucous Carcinoma of the Oral Cavity
Stage III Adenoid Cystic Carcinoma of the Oral Cavity
Stage III Mucoepidermoid Carcinoma of the Oral Cavity
Stage III Squamous Cell Carcinoma of the Hypopharynx
Stage III Squamous Cell Carcinoma of the Larynx
Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity
Stage III Verrucous Carcinoma of the Larynx
Stage III Verrucous Carcinoma of the Oral Cavity
Stage IV Squamous Cell Carcinoma of the Hypopharynx
Stage IVA Adenoid Cystic Carcinoma of the Oral Cavity
Stage IVA Mucoepidermoid Carcinoma of the Oral Cavity
Stage IVA Squamous Cell Carcinoma of the Larynx
Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity
Stage IVA Verrucous Carcinoma of the Larynx
Stage IVA Verrucous Carcinoma of the Oral Cavity
Stage IVB Adenoid Cystic Carcinoma of the Oral Cavity
Stage IVB Mucoepidermoid Carcinoma of the Oral Cavity
Stage IVB Squamous Cell Carcinoma of the Larynx
Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity
Stage IVB Verrucous Carcinoma of the Larynx
Stage IVB Verrucous Carcinoma of the Oral Cavity
Stage IVC Adenoid Cystic Carcinoma of the Oral Cavity
Stage IVC Mucoepidermoid Carcinoma of the Oral Cavity
Stage IVC Squamous Cell Carcinoma of the Larynx
Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity
Stage IVC Verrucous Carcinoma of the Larynx
Stage IVC Verrucous Carcinoma of the Oral Cavity
Tongue Cancer

Explore related trials

Adenoid Cystic CarcinomaBenign Head and Neck TumorMalignant Head and Neck NeoplasmMucoepidermoid CarcinomaSquamous Cell CarcinomaTongue CarcinomaVerrucous Carcinoma

Where it's being run

1 sites across 1 states
Ohio1

Study leadership

  • Enver Ozer, MD · PRINCIPAL_INVESTIGATOR · Ohio State University

Who to contact

Ohio State University Comprehensive Cancer Center
[email protected]
1-800-293-5066
Email the study team

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Eligibility criteria

Inclusion

Patient must present with indications for diagnostic or therapeutic approaches for benign and/or malignant diseases of the oral cavity or laryngopharynx (including the neoplastic lesions of the tongue, tongue base, retromolar trigone, tonsils, palate, posterior and lateral pharynx, glottic, supraglottic and subglottic larynx)
Patients must have adequate transoral exposure of the oral cavity and laryngopharynx for TORS instrumentation
Written informed consent and/or Consent waiver by institutional review board (IRB)

Exclusion

Unexplained fever and/or untreated, active infection
Patient pregnancy
Previous head and neck surgery that would preclude transoral/robotic procedures. This is at the investigator's discretion. This is not an exclusion criterion for the non-surgical arm.
The presence of medical conditions contraindicating general anesthesia or transoral surgical approaches
Inability to grant informed consent
Inability to adequately visualize anatomy to perform the diagnostic or therapeutic surgical approach transorally

What this trial measures

  • Determine the feasibility of the TORS in patients with oral and laryngopharyngeal benign and malignant lesions.up to eight years