Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

This study is looking at how stereotactic radiosurgery (SRS) affects the quality of life and tremor severity for people with essential tremor or Parkinsonian tremor. SRS is a treatment that uses focused radiation to target the part of the brain causing tremors. You might be able to join if a neurologist confirms your tremor isn't well-controlled by medication and you prefer radiation treatment over surgery like deep brain stimulation (DBS) or thalamotomy. The study will measure changes in your tremor-related quality of life after one year using questionnaires. The study is currently unclear on its status and aims to enroll 60 participants.

Study design
This is an observational study, meaning researchers will collect information without giving you a specific treatment. It plans to include 60 participants.
What's involved
You will complete questionnaires and observational assessments, including QUEST, PDQ-39, FTM, and a Neuropsych evaluation.
Compensation
Not stated in the trial record.
Follow-up
Your tremor-related quality of life will be measured at 1 year after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT01734122

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

Recruiting
Not specifiedAges 18+Observational
Vanderbilt University Medical Center
~60 participants
Updated 2025-09-12 on ClinicalTrials.gov
What's tested:Questionnaires / Observational Assessments

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Tremor-related Quality of Life
Measured over 1 year
Tremor
Essential Tremor
Parkinson Disease
Radiosurgery
Quality of Life
1 sites across 1 states
Tennessee1
Send Patient Referrals to Movement Disorder Coordinators
Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Must be certified by a neurologist as having essential tremor or Parkinsonian tremor that is insufficiently controlled by medication alone.
Preference to receive radiation treatment for tremor treatment, rather than surgical DBS implantation or surgical thalamotomy
At least 18 years old

Exclusion

Contraindications to cranial radiation (such as prior radiation to the thalamus)
Inability to have a MRI of the brain
Prior surgical thalamotomy treatment (but contralateral deep brain stimulator \[DBS\] is permitted)
Estimated life expectancy less than 1 year
  • Tremor-related Quality of Life1 year

    The tremor-related quality of life for each patient will be assessed by self-assessment questionnaire at 3 month intervals for 1 year after treatment by stereotactic radiation.