Observational Study of Cardiac MRI in Sarcoidosis

This observational study is looking at how well a special type of MRI, called Cardiovascular Magnetic Resonance (CMR), can find heart problems in people with sarcoidosis. Sarcoidosis is a disease that can affect many organs, and sometimes it affects the heart without being noticed. The study wants to see if CMR can detect these heart issues better than standard check-ups. You might be able to join if you are 18 or older, have sarcoidosis confirmed by a biopsy, and your doctor suspects you might have sarcoidosis affecting your heart. The study aims to determine if using CMR can help reduce deaths from heart problems, irregular heartbeats (arrhythmic death), or lung problems (pulmonary mortality) in people with sarcoidosis. The study status is currently unclear, and it plans to include 27,000 participants.

Study design
This is an observational study with a planned enrollment of 27,000 participants. It is not a randomized trial, meaning participants will not be assigned to different treatment groups.
What's involved
Patients will undergo Cardiovascular Magnetic Resonance (CMR) in addition to their routine clinical evaluation.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for cardiac mortality, arrhythmic death, and pulmonary mortality for more than 1 year.

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NCT01745237

Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis

Recruiting
Not specifiedAges 18+Observational
Duke University
~27,000 participants
Updated 2025-04-13 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
cardiac mortality
Measured over > 1year
+2 more outcomes measured
Sarcoidosis
1 sites across 1 states
North Carolina1
  • Raymond J Kim, MD · PRINCIPAL_INVESTIGATOR · Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center

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Eligibility criteria

Inclusion

Biopsy proven sarcoidosis
Suspected cardiac sarcoidosis

Exclusion

Contraindication to MRI
  • cardiac mortality> 1year
  • arrhythmic death> 1year
  • Pulmonary mortality> 1year

    only in subset of patients with pulmonary sarcoidosis