This observational study aims to better understand why some men with prostate cancer don't respond as well to initial radiation treatments. Radiation therapy is a common treatment, but for a small number of men, the cancer may return. This study will use advanced imaging (multiparametric prostate MR) and biopsies to find out how often prostate cancer comes back locally after radiation. This information is important because knowing if the cancer has returned only in the prostate can help doctors choose the best next steps. You may be able to join if you are a man aged 18 or older with newly diagnosed, untreated prostate cancer that is considered intermediate or high-risk, and you are planning to receive radiation therapy. The study will measure the rate of local recurrence (cancer returning in the prostate) at the end of the study.

Study design

This is an observational study planning to include 300 men. It is not testing a new treatment but rather observing how prostate cancer responds to standard radiation therapy.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint, local recurrence, will be measured at the completion of the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.