Electrical Impedance Myography for Neuromuscular Disorders

This study is exploring a new technique called Electrical Impedance Myography (EIM) to help understand muscle and nerve conditions. EIM uses a mild, painless electrical current to see how it travels through muscles. Researchers want to learn more about how EIM works in people with neuromuscular diseases (conditions affecting nerves and muscles) and healthy volunteers. They will compare EIM results with other standard tests like nerve and muscle ultrasonography, nerve conduction studies (which measure how fast nerves send signals), and electromyography (EMG, which records muscle electrical activity). The goal is to see if EIM can help tell different neuromuscular disorders apart and if it could be used to track changes over time. Adults and children aged 2 to 110 years can participate.

Study design
This is an interventional study with a planned enrollment of 275 participants, including both healthy volunteers and individuals with neuromuscular disorders.
What's involved
You would undergo EIM testing, nerve and muscle ultrasonography, and nerve conduction studies. Adults may also have electromyography (EMG).
Compensation
Not stated in the trial record.
Follow-up
EIM measures for muscles will be taken at the end of the study for both patients and healthy volunteers.

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NCT01900132

Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers

Recruiting
NAAges 2+InterventionalBasic science
National Institute of Neurological Disorders and Stroke (NINDS)
~275 participants
Updated 2026-08-04 on ClinicalTrials.gov
What's tested:EIM testingNerve & muscle ultrasonographyNerve conduction studiesElectromyography (EMG)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patients - EIM measures for a selection of muscles
Measured over End of study
+1 more outcome measured
Neuromuscular Disease
Motor Neuron Disease
Inherited Neuromuscular Conditions
Inherited Neuropathies
1 sites across 1 states
Maryland1
  • Tanya J Lehky, M.D. · PRINCIPAL_INVESTIGATOR · National Institute of Neurological Disorders and Stroke (NINDS)

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  • Patients - EIM measures for a selection of musclesEnd of study

    Obtaining measures using EIM device in different types of neuromuscular disorders.

  • Healthy Volunteers - EIM measures for a selection of muscles with the aim of developing normative values for the NIH EMG labEnd of study

    Obtaining measures using EIM device- reproducibility and normative data