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Observational Study of Mesothelioma and Other Cancers

This is an observational study focused on collecting tissue samples from patients with malignant mesothelioma and other cancers that express mesothelin (a protein found on the surface of some cancer cells). The goal is to gather samples to better understand these diseases. You may be able to join if you are at least 2 years old with malignant mesothelioma, or at least 18 years old with thymic carcinoma, pancreatic, biliary, lung, gastric, or ovarian cancers, or other solid tumors known to express mesothelin. A confirmed diagnosis from a pathologist is required. This study aims to acquire samples on an ongoing basis.

Study design
This is an observational study with a planned enrollment of 1000 participants. It is not testing a specific intervention or drug.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT01950572

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

Recruiting
Not specifiedAges 2+Observational
National Cancer Institute (NCI)
~1,000 participants
Updated 2026-08-26 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
sample aquisition
Measured over Ongoing

Conditions

Thymoma
Stomach Neoplasms
Pancreatic Neoplasms
Mesothelioma
Biliary Tract Neoplasms
Mesothelin Expressing Neoplasms

Explore related trials

Gastric NeoplasmLung NeoplasmMesothelial NeoplasmNeoplasm of biliary tractOvarian NeoplasmPancreatic NeoplasmSolid NeoplasmThymomaMesothelin

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Raffit Hassan, M.D. · PRINCIPAL_INVESTIGATOR · National Cancer Institute (NCI)

Who to contact

Cathy I Wagner, R.N.
[email protected]
(240) 858-3159
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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

All participants \>= 2 years of age with malignant mesothelioma.
All participants \>=18 years of age with thymic carcinoma, pancreatic or biliary adenocarcinoma or lung, gastric or ovarian cancers or other solid tumor known to express mesothelin.
Confirmed pathological diagnosis is required
Ability and willingness of participant to provide informed consent to participation.

Exclusion

Active symptomatic major organ disorder that would increase the risk of biopsy, including but not limited to ischemic heart disease, recent myocardial infarction, active congestive heart failure, pulmonary dysfunction.
Pregnant women.
Active concomitant medical or psychological illnesses that may increase the risk to the participant or in adult participants, inability to obtain informed consent, at the discretion of the principal investigator.

What this trial measures

  • sample aquisitionOngoing

    allow sample acquisition for use in the study of mesothelioma