Long-Term Follow-Up for Islet Transplant Recipients
This observational study is following 30 adults (ages 18-65) who have already received a successful pancreatic islet transplant for Type 1 Diabetes Mellitus. The study aims to understand how long these islet transplants continue to work well. You can join if you participated in one of several previous islet transplant studies, still have a working islet graft, and are willing to use contraception during and for four months after the study. The main goal is to measure how long the islet graft continues to function over a period of three years. This study is not testing a new treatment, but rather observing the long-term effects of previous islet transplant procedures.
- Study design
- This is an observational study with an unclear status, planning to enroll 30 participants. It is not testing a new intervention but rather observing participants over time.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed to measure the duration of sustained islet allograft function for up to 3 years.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Long Term Follow up of Recipients of Functional Islet Allografts
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Rodolfo Alejandro, MD · PRINCIPAL_INVESTIGATOR · University of Miami
Who to contact
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What this trial measures
- Duration of sustained islet allograft function3 years
The primary endpoint is duration of sustained islet allograft function as determined by evidence from Mixed Meal Tolerance Test of c-peptide production. A c-peptide level \>=0.3 ng/ml at 0, 60, or 90 minutes will be considered evidence of islet allograft function.