Integrated Cancer Repository for Cancer Research (iCaRe2)

This observational study, called the Integrated Cancer Repository for Cancer Research (iCaRe2), is collecting health information and biological samples (like tissue or blood) from adults with or at risk for certain cancers, including pancreatic, thyroid, lung, esophageal, and thymus cancer. It also includes healthy individuals as a comparison group. The goal is to create a large resource to help researchers better understand cancer development and progression, and to design new ways to prevent, screen for, detect, and treat cancer. The study aims to develop and implement a web-based registry to manage this information.

Study design
This is an observational study, meaning researchers will collect information without giving any specific treatments. It aims to enroll a very large number of participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary goal of developing the web-based registry is measured over 86 years, suggesting a very long-term collection of data.

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NCT02012699

Integrated Cancer Repository for Cancer Research

Recruiting
Not specifiedAges 19+Observational
University of Nebraska
~999,999 participants
Updated 2026-06-29 on ClinicalTrials.gov

At a glance

Recruiting sites
42 of 42 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Development and Implementation of a Web-based Cancer Collaborative Registry
Measured over 86 years
Pancreatic Cancer
Thyroid Cancer
Lung Cancer
Esophageal Cancer
Thymus Cancer
Colon Cancer
Rectal Cancer
Gastrointestinal Stromal Tumors
Anal Cancer
Bile Duct Cancer
Duodenal Cancer
Gallbladder Cancer
Gastric Cancer
Liver Cancer
Small Intestine Cancer
Peritoneal Surface Malignancies
Familial Adenomatous Polyposis
Lynch Syndrome
Bladder Cancer
Kidney Cancer
Penile Cancer
Prostate Cancer
Testicular Cancer
Ureter Cancer
Urethral Cancer
Hypopharyngeal Cancer
Laryngeal Cancer
Lip Cancer
Oral Cavity Cancer
Nasopharyngeal Cancer
Oropharyngeal Cancer
Paranasal Sinus Cancer
Nasal Cavity Cancer
Salivary Gland Cancer
Skin Cancer
Central Nervous System Tumor
Central Nervous System Cancer
Mesothelioma
Breast Cancer
Leukemia
Melanoma
Sarcoma
Unknown Primary Tumor
Multiple Myeloma
Ovarian Cancer
Endometrial Cancer
Vaginal Cancer
Neuroendocrine Tumors
Plasma Cell Dyscrasia
Healthy Control
42 sites across 18 states
Missouri6
Nebraska6
Florida5
Minnesota5
Illinois2
Iowa2
Maryland2
New York2
  • Kurt Fisher, MD, PhD · PRINCIPAL_INVESTIGATOR · University of Nebraska

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Eligibility criteria

Inclusion

Diagnosis/history of cancer
Risk for developing cancer or suspicious clinical findings
No history of cancer (normal control registry)
Able to provide informed consent
19 years of age or older
English or Spanish speaking individuals

Exclusion

Unable to provide informed consent because of cognitive impairment
Non-English or non-Spanish speaking individuals
  • Development and Implementation of a Web-based Cancer Collaborative Registry86 years

    This is a registry that will continue to accrue participants indefinitely.