Observational Study of Metabolic Responses to Bariatric Surgery
This observational study is looking at how bariatric surgery (weight loss surgery) affects the body's metabolism in people with morbid obesity. Researchers will collect small samples of fat during your surgery, along with blood, urine, and stool samples before and after surgery. They want to understand the genetic and biomechanical markers (signs in your body) in fat tissue. You might be able to join if you are between 18 and 55 years old, meet NIH criteria for bariatric surgery, and have controlled dyslipidemia (unhealthy cholesterol levels) or impaired glucose metabolism (how your body uses sugar) or type 2 diabetes. The main goal is to measure the strength of white adipose tissue (fat tissue). The study status is unclear, and it aims to include 500 participants.
- Study design
- This is an observational study, meaning researchers will collect information without giving you a specific treatment. It aims to include 500 participants.
- What's involved
- You would complete pre-operative labs, testing, and counseling. During surgery, tissue samples will be collected. Blood, urine, and fecal samples will be collected before surgery, and additional blood/urine samples will be collected during post-surgery lab visits.
- Compensation
- Not stated in the trial record.
- Follow-up
- You will be observed for weight loss and resolution of other health conditions after surgery, with additional blood/urine samples collected at designated times post-surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Metabolic Responses to Bariatric Surgery
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Mohamed R Ali, MD · PRINCIPAL_INVESTIGATOR · University of California Davis Health System
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Tensile Strength of White Adipose TissueJuly 2012
During the research tissue samples were compared between healthy obese patients (no diabetes, controlled HTN, no dyslipidemia) with tissue samples collected on non-healthy obese patients (type II diabetes) and using fat collected from mice as a control.