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Kidney Cancer DNA Registry

This study is creating a registry (a collection of information) to help us better understand kidney cancer. We are collecting saliva for germline DNA (your inherited genetic material), blood samples, and asking participants to complete questionnaires about kidney cancer, their family history, and general health. This information will help researchers develop better ways to prevent, diagnose, and treat kidney cancer. You may be able to join if you are 18 or older, speak English, and have a diagnosis or suspicion of kidney cancer. Family members of those with kidney cancer who are 18 or older, speak English, and are blood relatives can also participate. The goal is to establish this registry over five years.

Study design
This is an observational study, meaning participants are observed without receiving a specific treatment. The study plans to enroll 750 participants.
What's involved
You would provide a saliva sample, a blood sample, and complete several questionnaires (Kidney Cancer Questionnaire, Family History Questionnaire, Epidemiologic Questionnaire) either in the office or online.
Compensation
Not stated in the trial record.
Follow-up
The primary goal is to establish the registry, measured at 5 years. It is not specified if individual participants will have follow-up after their initial participation.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT02087852

Kidney Cancer DNA Registry

Recruiting
Not specifiedAges 18+Observational
Memorial Sloan Kettering Cancer Center
~750 participants
Updated 2026-04-09 on ClinicalTrials.gov
What's tested:salvia for germline DNAthe Kidney Cancer QuestionnaireFamily History Questionnaire (when applicable)Blood drawEpidemiologic Questionnaire

At a glance

Recruiting sites
7 of 7 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
establish a kidney cancer registry
Measured over 5 years

Conditions

Renal Cancer

Explore related trials

Kidney Carcinoma

NCT02087852

Where you'd take part

This study runs at 7 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Memorial Sloan Kettering at Basking Ridge (Consent and Follow-up)

    Basking Ridge, New Jerseystudy coordinator listed

    Recruiting

  • Memorial Sloan Kettering Bergen (Consent and Follow up )

    Montvale, New Jerseystudy coordinator listed

    Recruiting

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New Yorkstudy coordinator listed

    Recruiting

  • Memorial Sloan Kettering Commack (Consent and Follow-up)

    Commack, New Yorkstudy coordinator listed

    Recruiting

  • Memorial Sloan Kettering Monmouth (Consent and Follow up)

    Middletown, New Jerseystudy coordinator listed

    Recruiting

  • Memorial Sloan Kettering Nassau (Consent and Follow-Up)

    Uniondale, New Yorkstudy coordinator listed

    Recruiting

  • Memorial Sloan Kettering Westchester (Consent and Follow up)

    Harrison, New Yorkstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Jonathan Jonathan, MD · PRINCIPAL_INVESTIGATOR · Memorial Sloan Kettering Cancer Center

Who to contact

Jonathan Coleman, MD
646-422-4432
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Eligibility criteria

Inclusion

Must be ≥ 18 years of age AND
Must be an English-speaker AND
Must have a diagnosis or suspicion of kidney cancer
Must be ≥ 18 years of age AND
Must be an English-speaker AND
Must be a blood relative of the proband. Family members of probands including mother, father, sisters, brothers, half-sisters, half-brothers, daughters, sons, grandmothers, grandfathers, as well as aunts and uncles are eligible. These individuals need not have kidney cancer, as they will be used for segregation analysis of suspected variants found in the proband; requesting DNA from relatives is required.
Must be ≥ 18 years of age AND
Must be an English-speaker AND
Must not have a personal history of cancer, with the exception of nonmelanoma skin cancer, AND
Must not be a blood relative of any cases or controls enrolled in this study

Exclusion

Patients who, in the opinion of the primary MSKCC clinician or the investigator, have a condition that precludes their ability to provide an informed consent

What this trial measures

  • establish a kidney cancer registry5 years

    with detailed epidemiologic data and germline DNA available for next generation sequencing from consenting patients, selected family members, and healthy unrelated controls.