Understanding Quality of Life After Rectal Cancer Surgery

This study is looking at how quality of life changes for people who have had surgery for stage I-IV rectal cancer (cancer that starts in the rectum, the last part of the large intestine). Researchers want to understand how different treatments, like radiation therapy, affect your well-being over time. You would complete questionnaires about your quality of life. The main goal is to measure your health and well-being 24 months after surgery. This study is for adults aged 18 and older who have been diagnosed with rectal adenocarcinoma and are planning to have or have already had surgery with the goal of a cure. The study is currently unclear on its recruitment status.

Study design
This is an observational study, meaning researchers will watch and collect information without giving new treatments. It plans to include 430 participants.
What's involved
You would complete quality of life questionnaires at baseline (before or soon after surgery), then at 6 and 12 months after surgery, and again at 2, 3, 4, and 5 years after surgery. Each questionnaire takes 20-30 minutes.
Compensation
Not stated in the trial record.
Follow-up
Participants are followed for up to 5 years after surgery, with the primary measurement taken at 24 months post-surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT02107105

Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~430 participants
Updated 2026-04-06 on ClinicalTrials.gov
What's tested:Quality-of-Life AssessmentQuestionnaire Administration

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Health state utilities
Measured over At 24 months post-surgery
Rectal Adenocarcinoma
Stage I Rectal Cancer AJCC v8
Stage II Rectal Cancer AJCC v8
Stage IIA Rectal Cancer AJCC v8
Stage IIB Rectal Cancer AJCC v8
Stage IIC Rectal Cancer AJCC v8
Stage III Rectal Cancer AJCC v8
Stage IIIA Rectal Cancer AJCC v8
Stage IIIB Rectal Cancer AJCC v8
Stage IIIC Rectal Cancer AJCC v8
Stage IV Rectal Cancer AJCC v8
Stage IVA Rectal Cancer AJCC v8
Stage IVB Rectal Cancer AJCC v8
Stage IVC Rectal Cancer AJCC v8
1 sites across 1 states
Texas1
  • George J Chang · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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Eligibility criteria

Inclusion

Patient has histologically proven adenocarcinoma of the rectum (stage I - IV) that is planned to be treated by surgical resection performed with curative intent, or who has already received surgical treatment
Patient must sign an approved informed consent document and have the literary and physical ability to complete the questionnaire in English

Exclusion

Patient has been treated with pelvic radiation therapy for a diagnosis other than rectal cancer
Patient has a concurrent cancer diagnosis at the time of consent
Patient has recurrent disease
  • Health state utilitiesAt 24 months post-surgery

    A health state utility is the degree of preference that individuals or society has for a particular health state or condition.