Developing Behavioral Tasks for Alcohol Use Disorder Research

This study aims to create and test new tasks that measure specific thinking, motivation, and decision-making behaviors in people with and without alcohol use disorder. Researchers want to use a special type of MRI scan called 7T MRI to see how these tasks affect brain activity. The goal is to develop reliable tasks that can be used in future studies to better understand how alcohol use disorders impact the brain and behavior. This study is looking for up to 400 participants, aged 18 to 65, who are either healthy volunteers or inpatients with alcohol dependence. Success for this study means developing tasks that consistently measure these behaviors and show related brain activity.

Study design
This interventional study plans to enroll up to 400 participants. It involves developing and testing tasks both outside and inside a scanner.
What's involved
You would undergo a medical history review, physical exam, EKG, blood and urine tests, and a psychiatric interview. You would also pilot one or both aspects of the study's tasks.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome of developing and examining tasks is measured on an ongoing basis.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT02108054

Behavioral and Functional Task Development, Implementation, and Testing

Recruiting
NAAges 18–65Interventional
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
~400 participants
Updated 2026-06-30 on ClinicalTrials.gov
What's tested:7T MRI

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
outcome is to develop and examine tasks that reliably measure specific cognitive, motivational and decision-making behaviors
Measured over ONGOING
Alcohol Dependence
Alcohol Drinking
Alcoholism
Alcohol Use Disorder
Addiction
1 sites across 1 states
Maryland1
  • Paule V Joseph, C.R.N.P. · PRINCIPAL_INVESTIGATOR · National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Exclusion

Are not cleared on a neuromotor examination
Are currently receiving psychotropic medication
Inpatients only: Currently experiencing symptoms of withdrawal from alcohol (As determined by the most recent measurement within the
Presence of ferromagnetic objects in the body including implanted pacemakers, medication pumps, aneurysm clips, metallic prostheses (including metal pins and rods, heart valves or cochlear implants), shrapnel fragments, permanent eye liner or small metallic fragments in the eye that welders and other metal workers may have;
Are pregnant, as determined by a negative pregnancy test
Left handed
Claustrophobia.
To minimize discomfort and undue burden on the participants, unless available from phone screening, pre-screening, or other NIAAA studies such as 14-AA-0080, 14-AA-0181, we collect the above information as part of this study.
  • outcome is to develop and examine tasks that reliably measure specific cognitive, motivational and decision-making behaviorsONGOING

    Tasks that are suitable for fMRI studies and other clinical research measurements