This study is looking at different medications used to treat shock in patients in the intensive care unit (ICU). Researchers are comparing four drugs: norepinephrine, epinephrine, phenylephrine, and vasopressin. The main goal is to see if phenylephrine and vasopressin cause fewer fast or irregular heartbeats (tachydysrhythmias) compared to norepinephrine and epinephrine. This study is for adults aged 18 and older who need these medications for shock that hasn't improved with IV fluids. The study will measure how many patients die in the hospital up to six months after treatment. The current status of this study is unclear, and it plans to include 836 participants.

Study design

This is a randomized, double-blind controlled trial comparing two groups of vasoactive drugs. It plans to enroll 836 participants.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed to measure hospital mortality up to six months.

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