NCT02151175

Low-intensity Focused Ultrasound Pulsation (LIFUP) for Treatment of Temporal Lobe Epilepsy

Enrolling by Invitation
NAAges 18–60InterventionalBasic science
BrainSonix Inc.
~12 participants
Updated 2024-08-06 on ClinicalTrials.gov
What's tested:LIFUP

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Absence of histological changes
Measured over 7 days
Epilepsy, Temporal Lobe
1 sites across 1 states
California1

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Subjects with clinical evidence from their diagnostic evaluations of unilateral hippocampal dysfunction and epileptogenicity.
Subjects with seizures that have been refractory to treatment with at least three currently marketed antiepileptic drugs.
Subjects with epilepsy who would clearly benefit from surgical intervention.
Subjects who have been offered a non-dominant anterior-mesial temporal lobe resection as treatment for medication refractory epilepsy.

Exclusion

Subjects with a cognitive or psychiatric disorder that limits the ability to give informed consent or are unable to cooperate with the testing.
Subjects with dementia, delirium and psychotic symptoms. - Subjects with ferromagnetic materials in the head.
Subjects with severe cardiac disease, increased intracranial pressure, or a TENS unit.
Subjects who exhibit primary generalized seizures or pseudoseizures.
Subjects who have seizures secondary to drugs, alcohol, metabolic illness or progressive degenerative disease.
Subjects who have experienced status epilepticus during the 3-week baseline period prior to the operation.
Subjects (females) who are pregnant.
  • Absence of histological changes7 days