Ketogenic Therapy for Seizures Study

This study is looking at how Ketogenic Therapy, a special diet high in fat and low in carbohydrates, affects seizures. Many children with seizures don't respond well to current treatments, and while Ketogenic Therapy has been used for a long time, doctors are still learning the best way to use it and how it works. This study will gather information on how well Ketogenic Therapy reduces seizures and if it causes any side effects like changes in growth or cholesterol levels. You may be able to join if your doctor has prescribed the ketogenic diet, your lab tests show you can metabolize a high-fat, low-carbohydrate diet, and you can follow the diet and keep records. The study is planned to include 400 participants aged 0 to 50 years old, but its current status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment (Ketogenic Therapy). It aims to enroll 400 participants.
What's involved
You would need to be compliant with administering the therapy and with record keeping. The study will also involve lab tests to check your ability to metabolize the diet.
Compensation
Not stated in the trial record.
Follow-up
The study will measure reduced seizures at 2 years.

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NCT02216500

Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy

Recruiting
NAUp to 50InterventionalTreatment
University of Florida
~400 participants
Updated 2025-07-11 on ClinicalTrials.gov
What's tested:Ketogenic Therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Reduced seizures
Measured over 2 years
Seizures
1 sites across 1 states
Florida1
  • Peggy R. Borum, Ph.D. · PRINCIPAL_INVESTIGATOR · University of Florida

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Eligibility criteria

Inclusion

Patients whose physician has prescribed the ketogenic diet
Patients with lab tests consistent with the ability to metabolize a high fat and low carbohydrate diet
Patients that can be compliant with administration of the therapy and with record keeping.

Exclusion

Patients with lab tests consistent with the inability to metabolize a high fat and low carbohydrate diet
Patients at risk of being non-compliant with administration of the therapy and with record keeping
  • Reduced seizures2 years

    Seizures will be charted from collected data.