Gabapentin and Oxcarbazepine for Pediatric Chronic Neuropathic Pain
This study is looking at how well two medications, Gabapentin and Oxcarbazepine, work to reduce chronic neuropathic pain (pain from nerve damage) in children and teenagers. Participants aged 8 to 18 with chronic neuropathic pain will be randomly assigned to receive either Gabapentin or Oxcarbazepine. Neither you nor the study team will know which medication you are receiving (this is called "blinded"). The study will measure if your pain significantly decreases from your starting pain level. The goal is to see how often these treatments successfully reduce pain. The study aims to enroll 60 participants, but its current recruitment status is unclear.
- Study design
- This is a randomized, double-blind study comparing two treatments, Gabapentin and Oxcarbazepine, in children and adolescents. It plans to enroll 60 participants.
- What's involved
- Pain scores will be measured at the start of the study, and then at 2, 4, 6, and 8 weeks after starting the medication.
- Compensation
- Not stated in the trial record.
- Follow-up
- Pain levels will be monitored for 8 weeks after starting the assigned medication.
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Gabapentin and Oxcarbazepine for Chronic Neuropathic Pain in Children and Adolescents: A Clinical Effectiveness Study
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Monique Ribeiro, MD · PRINCIPAL_INVESTIGATOR · Boston Children's Hospital
Who to contact
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What this trial measures
- As a primary outcome, success will be defined by clinically and statistically significant within subject reductions in pain scores0 (baseline), 2, 4, 6, 8 weeks (post-assignment of intervention)
1. 2 point reduction in average daily pain scores 2. 30% reduction relative to baseline 3. Global overall impression of strong benefit.