Breast Tumor Tissue Repository for Cancer Research

This study is creating a collection (repository) of breast tumor tissue samples from core biopsies. By collecting these samples, doctors hope to learn more about how breast cancer grows and responds to treatments. This information could help develop better therapies and tests to guide treatment decisions in the future. You may be able to join if you are 18 or older and have known or suspected breast cancer, or a metastatic solid tumor (cancer that has spread) that originated in the breast. The study aims to develop this tissue bank and a secure database of information about the samples, and to create an efficient way for researchers to use these de-identified (anonymized) samples for breast cancer studies. The current recruitment status is unclear.

Study design
This is an observational study, meaning it collects information without assigning specific treatments. It plans to enroll up to 400 participants.
What's involved
You would undergo core needle biopsies of breast cancer in the breast, regional lymph nodes, and distant metastases, if applicable. Clinical and blood specimens would also be gathered.
Compensation
Not stated in the trial record.
Follow-up
The study aims to develop and maintain the repository and database for up to 10 years.

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NCT02250352

Core Biopsies for Establishing a Breast Tumor Tissue Repository

Recruiting
Not specifiedAges 18+Observational
University of Southern California
~400 participants
Updated 2026-05-13 on ClinicalTrials.gov
What's tested:cytology specimen collection procedure

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Development of a baseline and serial breast cancer core biopsy repository within the USC/Norris Comprehensive Cancer Center Women's Cancer Program
Measured over Up to 10 years
+2 more outcomes measured
Breast Cancer
1 sites across 1 states
California1
  • Evanthia Roussos-Torres, M.D. · PRINCIPAL_INVESTIGATOR · University of Southern California

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Eligibility criteria

Inclusion

Known or suspected breast cancer
Known or suspected metastatic solid tumor that originated in the breast per the patient's medical history

Exclusion

Inability to sign informed consent
Known bleeding disorder
Use of anticoagulant medications (heparin, warfarin, etc.) within one week prior to biopsy
Use of antiplatelet medications (aspirin, clopidogrel, etc.) within one week prior to biopsy
  • Development of a baseline and serial breast cancer core biopsy repository within the USC/Norris Comprehensive Cancer Center Women's Cancer ProgramUp to 10 years
  • Development and maintenance of a secure clinical database of relevant demographic, clinical, pathologic, and longitudinal outcome characteristics of the samples to be bankedUp to 10 years
  • Development of an efficient process for the distribution of de-identified samples from the bank to researchers with IRB-approved protocols or exemptions for the study of breast cancer-related questionsUp to 10 years