Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults
This study is testing a new way to look at lung function using a special type of gas called hyperpolarized 129 Xenon (HP 129Xe) during an MRI scan. Researchers want to see if this method can accurately measure how well your lungs are working, both in healthy people and in those with breathing problems. You might be able to join if you are 6 years or older and can hold your breath for up to 16 seconds. You cannot join if you have certain heart conditions, are pregnant, or have uncontrolled asthma. The main goal is to compare the lung measurements from the HP 129Xe MRI with standard MRI results. The current recruitment status is unclear, but the study plans to enroll 300 participants.
- Study design
- This is an interventional study planning to enroll 300 participants aged 6 and up. It is not specified if it is randomized or blinded.
- What's involved
- You will inhale hyperpolarized Xenon gas for up to 16 seconds during up to four separate MRI scans on a single day. You will also have follow-up phone calls one day and 30 days after your MRI.
- Compensation
- Not stated in the trial record.
- Follow-up
- You will have follow-up phone calls one day and 30 days after your MRI date.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jason C. Woods, PhD · PRINCIPAL_INVESTIGATOR · Children's Hospital Medical Center, Cincinnati
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Correlation of ventilated volume predictions obtained with 129Xe MRI vs. 1H MRIDay 1
quantify the measurement agreement between the ventilated volume of healthy lungs predicted via 129 Xe MRI and the ventilated volume of the pleural cavity predicted via proton MRI